Hippopathway相关论文
The TEA domain (TEAD) family proteins (TEAD1-4) are essential transcription factors that control cell differentiation an......
Hippo signaling pathway was discovered for its critical role in organ growth control in multicellular organisms.Extensiv......
The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcr
Breast cancer is one of the most common malignancies in women.Of particular concern is triple negative breast cancer (TN......
Purpose: Oncogenic KIT or PDGFRA tyrosine kinase mutations are compelling therapeutic targets in most gastrointestinal s......
The steroid hormone 20-hydroxyecdysone(20E)and the serine/threonine Ste20-like kinase Hippo signal promote programmed ce......
The transcriptional coactivator Yes-associated protein(YAP)is frequently found dysregulated in various cancers.The oncog......
A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hemat
...
MOB1 protein is a core component of the Hippo signaling pathway in animals,where it is involved in controlling tissu......
目的探讨通过大肿瘤抑制因子2(LATS2)介导Hippo信号途径对小鼠骨髓间充质干细胞(BMSCs)生物学行为的调控效应。方法体外培养C57BL/6小......
目的探讨Hippo通路对小鼠骨髓间充质干细胞(BMSCs)向Ⅱ型肺泡上皮细胞(AECⅡ)分化、增殖、迁移能力的调控效应。方法采用直接贴壁法分......
目的 探讨刺参黏多糖抑制胰腺癌SW1990细胞增殖的可能机制.方法 应用8 mg/ml刺参黏多糖干预胰腺癌SW1990细胞24、48、72 h,采用RT-......
Hippo pathway can regulate cell division,differentiation and apoptosis,and control the shape and size of organs.To study......
胃肠道间质瘤(gastrointestinal stromal tumors,GIST)是消化道中最常见的间叶组织来源实体瘤。大约85%的GIST存在酪氨酸激酶受体(......